These days scaling usually works even under Linux. However, there are always a few stubborn applications that evade scaling and unfortunately one of them is MPLAB X IDE I use for PIC microcontroller development.
While there are instructions on how to deal with it under Windows, it doesn't really explain how to get an equivalent behavior under Linux other than running executable directly.
But, you can use the same fontsize trick on Linux too and make your life easier by modifying the desktop file manually. Just run the following command:
sudo sed -i -E 's|Exec=(.*)mplab_ide.*|Exec=\1mplab_ide --fontsize 17|' \
/usr/share/applications/mplab_ide-v6.20.desktopAssuming your version is 6.20 (otherwise adjust as needed), you will get everything sized about 50% larger (default font size is 11). Now your eyes can finally relax.